Platelet Immunobiology

Aim

enable collaborations in platelet immunobiology by bringing together members working in a (diagnostic) laboratory, research and/or clinical setting

Platelet Immunobiology studies the pathogenic immune mechanisms responsible for platelet disorders related to alloantibodies or autoantibodies against platelets. Platelet disorders caused by antibodies against platelets include immune thrombocytopenia, fetal/neonatal alloimmune thrombocytopenia, drug-induced immune thrombocytopenia, and platelet-transfusion refractoriness. Rapid and precise diagnosis using reliable platelet serology testing is mandatory to avoid severe clinical consequences for patients. Understanding the underlying mechanisms is a key to better treatment or prophylaxis. 

 

 

About

We provide access to like-minded colleagues active in (diagnostic) laboratory, research and/or clinical settings in all aspects of platelet immunobiology. We promote basic and clinical research to improve the knowledge on antibody-mediated platelet disorders and to improve laboratory testing and clinical guidance. We set standards for serological testing, diagnostic pathways, and clinical decision making in patients with antibody-mediated platelet disorders. 

To reach our aims, we establish and monitor nomenclature for human platelet alloantigens (HPA) and support scientific co-operation between our members. We encourage and support new and emerging platelet immunology laboratories through education and organisation of practical workshop sessions. 

Our Chairpersons are Ulrich J. Sachs and Nelson H. Tsuno. 

Activities

We meet at ISBT congresses. We organise international workshops every other year. Also, we regularly organise the exchange of typing material and test protocols. We have installed sub-committees on Quality and Clinical Guidance and invite ISBT members with interest in the field to actively participate. 

Joining the WP

Membership is open to all ISBT members actively working in a (diagnostic) laboratory, research, or clinical setting of the field of Platelet Immunobiology. Employees of pharmaceutical companies are allowed to attend our meetings; however, they cannot become a WP member nor actively participate in a workshop.

Interested in joining the Platelet Immunobiology WP? Please email our Chairpersons (Ulrich J. Sachs) here or (Nelson H. Tsuno) here

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Meetings

Some of the content is only accessible for ISBT-members. To join us, click here.

FNAIT survey

Fetal and Neonatal alloimmune thrombocytopenia (FNAIT) is a severe bleeding disorder affecting fetuses and newborns. Patients have low platelet counts due to antibodies specific for human platelet antigens inherited from the father. In severe cases, intracranial haemorrhage could occur.

The ISBT Working Party on Platelet Immunobiology has drafted an electronic survey on FNAIT therapy. The goal of the survey is to help clinicians in management of patients and improve FNAIT therapy globally and survey results will therefore be of great importance.

To participate, neonatologists /gynaecologists /obstetricians can click here (free). The survey does not take more than 10min and all participants will be informed of the results of the survey by email.  

Contact: GĂ©rald BERTRAND, French Blood Services of Brittany "EFS": gerald.bertrand@remove-this.efs.sante.fr 

Thank you for your time.

GET IN TOUCH

Ulrich J. Sachs

Ulrich J. Sachs

Chairperson

E-mail
Justus Liebig University
Clinical Immunology & Transfusion Medicine
Giessen, Germany

Nelson Tsuno

Nelson Tsuno

Chairperson

E-mail
University of Tokyo
Transfusion Medicine
Tokyo, Japan

OTHER WORKING PARTIES