Red Cell Transfusion Thresholds for preterm infants: Finally some answers

13 Jul 2022

This Live Journal Club was held on July 13, 2022 by Ruchika Goel and Satyam Arora.

Aim of the webinar: The aim of the webinar was to discuss the findings/ outcomes of the two of the most recent and path breaking trials (TOP & ETTNO) in Neonatal Transfusions.

Level of education required (1-5): 3 - intermediate (practical application) and above

What prior knowledge is required?

Kirpalani H, Bell EF, Hintz SR, Tan S, Schmidt B, Chaudhary AS, et al. Higher or Lower Hemoglobin Transfusion Thresholds for Preterm Infants. N Engl J Med. 2020 Dec 31;383(27):2639-2651. doi: 10.1056/NEJMoa2020248. PMID: 33382931; PMCID: PMC8487591.
Franz AR, Engel C, Bassler D, et al. Effects of Liberal vs Restrictive Transfusion Thresholds on Survival and Neurocognitive Outcomes in Extremely Low-Birth-Weight Infants: The ETTNO Randomized Clinical Trial. JAMA. 2020;324(6):560–570. doi:10.1001/jama.2020.10690

Target audience: Neonatologists, Pediatricians, Transfusion Medicine physician, Blood bankers, Transfusion practitioners, master of PhD students and Scientists

The Speaker

Satyam Arora

ISBT Regional Director South East Asia, Clinical Transfusion Working Party Secretary, Additional Professor, Transfusion Medicine, Post Graduate Institute of Child Health, Noida, India

ISBT Regional Director South East Asia (2024-2028), Additional Professor, Transfusion Medicine, Post Graduate Institute of Child Health (PGICH), Noida, India

Dr Satyam Arora, MBBS, MD (Transfusion Medicine), CABP (AABB) completed his MD in 2012 from the prestigious Post Graduate Institute Medical Education and Research (PGIMER), Chandigarh, India. He established a pediatric transfusion-focused academic transfusion medicine department at a stand-alone children’s hospital (under the Government) in India and currently working there as an additional professor. He is presently working to establish a dedicated pediatric hematopoietic stem cell transplant and cell therapy centre at the same institute.
He has done various international rotations (observerships) in hematopoietic stem cell transplants (Cleveland Clinic, USA) and Cell Therapy (Centre for Cell and Gene Therapy, Baylor Medical Center, USA). He is a member of the Technical Resource Group (TRG) on blood transfusion services (BTS) under the Directorate General Health Services under the Government of India and an expert member of India's National Donor Vigilance Program. He has been a member of ISBT since 2012 and was a founder member, past chairperson and South-East Asia representative with the Young Professional Council (YPC) of ISBT. Presently he is secretary of the Clinical Transfusion Working Party, co-chair of the Pediatric Transfusions subgroup of ISBT and member of the Hemovigilance Working Party. He is the recipient of many prestigious awards such as “Dr Harold Gunson” Fellowship (2012), the ISBT TTID Working Party Travel Award for Young Scientists (2014), “Young Scientist Award” by the Indian Society of Transfusion Medicine 2021and “Narendra S Bagaria Award” by the Indian Society of Blood Transfusion and Immunohematology (2022). His areas of interest are pediatric transfusions, hematopoietic stem cell transplants, apheresis science and hemovigilance.

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