Best of Transfusion Evidence Library 2024
Talking Transfusion Podcast
Tune into the second episode of the Talking Transfusion Podcast!
Introduction
Welcome to the quarterly Transfusion Evidence Round-Up.
This is a collaboration between the International Society of Blood Transfusion (ISBT) and the Transfusion Evidence Library (TEL). We aim to highlight high quality evidence randomised controlled trials and systematic reviews about an internationally relevant subject in the field of Transfusion Medicine. All references are drawn from the Transfusion Evidence Library and, where relevant, Stem Cell Evidence.
This Transfusion Evidence Round-Up is sent to ISBT members and TEL subscribers, so if you are a subscriber to both mailing lists and receive it twice please bear with us until we can resolve this.
The Transfusion Evidence Library is produced by the Systematic Review Initiative (SRI) and funded by the four UK blood services. It is available free at the point of access providing a comprehensive and up-to-date database of high quality evidence in Transfusion Medicine.
Top 10 articles
The following 10 articles were selected from the Transfusion Evidence Library by 3 reviewers: Matt Poynton, Hans Van Remoortel and Lilian Karimi
Top article
Effectiveness of ferritin-guided donation intervals in whole-blood donors in the Netherlands (FIND'EM): a stepped-wedge cluster-randomised trial
Selected articles
Andexanet for factor Xa inhibitor-associated acute intracerebral hemorrhage. Connolly, S.J., et al. (2024). The New England Journal of Medicine.
Meta-analysis and metaregression of the treatment effect of intravenous iron in iron-deficient heart failure. Martens, P., et al. (2023). JACC: Heart Failure.
Prehospital tranexamic acid is associated with a survival benefit without an increase in complications: results of two harmonized randomized clinical trials. Mazzei, M., et al. (2024). The Journal of Trauma and Acute Care Surgery.
Two-year outcomes following a randomised platelet transfusion trial in preterm infants. Moore, C.M., et al. (2023). Archives of Disease in Childhood. Fetal and Neonatal Edition.
Darbepoetin alfa to reduce transfusion episodes in infants with haemolytic disease of the fetus and newborn who are treated with intrauterine transfusions in the Netherlands: an open-label, single-centre, phase 2, randomised, controlled trial. Ree, I.M.C., et al. (2023). The Lancet. Haematology.
Early cold stored platelet transfusion following severe injury: a randomized clinical trial. Sperry, J.L., et al. (2024). Annals of Surgery.
Liberal or restrictive transfusion strategy in patients with traumatic brain injury. Turgeon, A.F., et al. (2024). The New England Journal of Medicine.
Editorial Board
Matt Poynton
Matt Poynton is a haematologist working at Oxford University Hospitals in the UK. He was an NIHR Academic Clinical Fellow in haematology where he developed research interests in patient reported outcome measures (PROMs) and quality of life (QoL) in anaemia driven disorders. He is now completing a DPhil in Medical Sciences at the University of Oxford to further focus on these research interests. Matt is also interested in education and has also worked as an Education Fellow with NHS Blood and Transplant where, in collaboration with the Royal College of Pathology and NHS England, he developed and populated the transfusion content of the Pathology Portal - a new educational resource in transfusion medicine and transfusion science.
Hans Van Remoortel
Hans Van Remoortel holds a Master’s degree in Physiotherapy and Rehabilitation Sciences and earned his PhD in Biomedical Sciences with a doctoral thesis focused on physical activity and comorbidities in patients with COPD.
Since 2013, Hans has been the coordinating researcher of the Centre for Evidence-Based Practice team at the Belgian Red Cross, where he leads systematic reviews, primary research studies, and the development of evidence-based guidelines in two critical areas of blood banking: donor selection and patient blood management.
He has also been appointed as a professor of evidence-based policy at the Department of Public Health and Primary Care at the Catholic University of Leuven in Belgium. His work demonstrates a strong dedication to improving healthcare policy and practice. With his recent specialisation in Health Economics, Hans is eager to apply his expertise in decision modelling for health economic evaluations and critically assessing cost-effectiveness analyses to further contribute to evidence-based healthcare decision-making.
Lilian Karimi
Lilian Karimi is the Blood Satellite Coordinator from Meru County, Kenya, and has a medical laboratory science background. She has served in the county for several years on optimizing blood product availability and utilization, particularly in resource-limited settings. Karimi is excited to discuss the ‘Early Cold Stored Platelet Transfusion Following Severe Injury’ study in the Talking Transfusion podcast, and its potential to address key challenges in trauma care and platelet management, especially in resource-limited settings.
Systematic Research Initiative
The Systematic Review Initiative (SRI) is a clinical research group established in 2001 by NHS Blood and Transplant (NHSBT) and funded by the UK Blood Services. The primary objective of the SRI is to “develop the evidence base for the practice of transfusion medicine”, by undertaking systematic reviews and other evidence-based medicine research projects in the transfusion field. @sritransfusion
- Twitter:
- @sritransfusion
Transfusion Evidence Library
- Twitter:
- @transfusionlib
Stem Cell Evidence
Stem Cell Evidence is a comprehensive collection of high quality research relevant to haematopoietic stem cell transplantation, updated monthly. The most important articles in the field are highlighted in the Stem Cell Evidence Alert which is a newsletter emailed to subscribers. Stem Cell Evidence aims to be a key resource worldwide for medical practitioners, clinical researchers and policy makers. It is also intended to be of value to those planning new clinical trials in the field. It is produced by the Systematic Review Initiative and funded by the UK Blood Services and Oxford Biomedical Research Centre.
- Twitter:
- @evidencestemc
