World Anaemia Awareness Day 2025
Talking Transfusion Podcast
Tune into the third episode of the Talking Transfusion Podcast!
Introduction
Welcome to the quarterly Transfusion Evidence Round-Up.
This is a collaboration between the International Society of Blood Transfusion (ISBT) and the Transfusion Evidence Library (TEL). We aim to highlight high quality evidence randomised controlled trials and systematic reviews about an internationally relevant subject in the field of Transfusion Medicine. All references are drawn from the Transfusion Evidence Library and, where relevant, Stem Cell Evidence.
This Transfusion Evidence Round-Up is sent to ISBT members and TEL subscribers, so if you are a subscriber to both mailing lists and receive it twice please bear with us until we can resolve this.
The Transfusion Evidence Library is produced by the Systematic Review Initiative (SRI) and funded by the four UK blood services. It is available free at the point of access providing a comprehensive and up-to-date database of high quality evidence in Transfusion Medicine.
Top 10 articles
The following 10 articles were selected from the Transfusion Evidence Library by 3 reviewers: Aikaj Jindal, Joanna Loh and Rishiraj Sinha.
Top article
Safety and Efficacy of Hypoxia-Inducible Factor-Prolyl Hydroxylase Inhibitors vs. Erythropoietin-Stimulating Agents in Treating Anemia in Renal Patients (With or Without Dialysis): A Meta-Analysis and Systematic Review
Selected articles
Intravenous versus oral iron for anaemia among pregnant women in Nigeria (IVON): an open-label, randomised controlled trial, Afolabi, B.B., et al. (2024). The Lancet Global Health.
Effect of Minimization of Early Blood Sampling Losses Among Extremely Premature Neonates: A Randomized Clinical Trial, Balasubramanian, H., et al (2024). The Journal of Pediatrics.
Luspatercept versus epoetin alfa in erythropoiesis-stimulating agent-naive, transfusion-dependent, lower-risk myelodysplastic syndromes (COMMANDS): primary analysis of a phase 3, open-label, randomised, controlled trial, Della Porta, M.G., et al. (2024). The Lancet Haematology.
Effects of Individualized Anemia Therapy on Hemoglobin Stability: A Randomized Controlled Pilot Trial in Patients on Hemodialysis, Fuertinger, D.H., et al. (2024). Clinical Journal of the American Society of Nephrology.
Standard of Care Versus Octreotide in Angiodysplasia-Related Bleeding (the OCEAN Study): A Multicenter Randomized Controlled Trial, Goltstein, L.C.M.J., et al. (2024). Gastroenterology.
Effect of Preoperative Recombinant Human Erythropoietin on the Need for Blood Transfusion and Surgical Outcomes in Adult Patients Undergoing Cardiac Surgery: A Systematic Review and Meta-Analysis with Trial Sequential Analysis, Hakim, S.M., Ahmad, A.H.M., and Amer, A.M., (2024). Journal of Cardiothoracic and Vascular Anesthesia.
Interventions for reducing red blood cell transfusion in adults undergoing hip fracture surgery: an overview of systematic reviews, Lewis, S.R., et al. (2023). Cochrane Database of Systematic Reviews.
Darbepoetin alfa to reduce transfusion episodes in infants with haemolytic disease of the fetus and newborn who are treated with intrauterine transfusions in the Netherlands: an open-label, single-centre, phase 2, randomised, controlled trial, Ree, I.M.C., et al. (2023). The Lancet Haematology.
Pharmacotherapy for Reducing RBC Transfusion for Patients in the ICU: A Systematic Review and Network Meta-Analysis, Yoshihiro, S., et al. (2024). Critical Care Medicine.
Editorial Board
Joanna Loh
Dr Joanna Loh is a specialist clinical and laboratory haematologist, completing her undergraduate and postgraduate medical training in Melbourne. In 2024, she completed a fellowship in red blood cell disorders in Toronto General Hospital which is the largest centre for haemoglobinopathies in North America. She also has an interest in obstetric haematology. She currently holds a research fellow position with the Transfusion Research Unit, Monash University, implementing the National Transfusion Dataset and completing work on massive transfusion. Her other research areas include hemoglobinopathies, obstetric haematology, thrombotic microangiopathy and global health/implementation science.
Rishiraj Sinha
Dr Rishiraj Sinha is a Senior Resident Doctor at All India Institute of Medical Sciences (AIIMS), New Delhi, India specialised in Transfusion Medicine with a 5.5-year MBBS program followed by a three-year MD residency at one of India's leading medical institutions at All India Institute of Medical Sciences (AIIMS) Bhopal. His mission is to guide and educate physicians and develop in-depth skills in transfusion medicine, expertise to treat patients, and support other physicians and technical staff in delivering optimal transfusion medicine-related care and also the transfusion medicine physicians in training focus on implementing their knowledge in support of direct and indirect patient and donor care. He is eager to engage in clinical and research activities, particularly in areas such as immunohaematology, transfusion safety, apheresis, and novel therapies like stem cell transplantation, where his enthusiasm and experience can contribute to innovative advancements in the field.
Systematic Research Initiative
The Systematic Review Initiative (SRI) is a clinical research group established in 2001 by NHS Blood and Transplant (NHSBT) and funded by the UK Blood Services. The primary objective of the SRI is to “develop the evidence base for the practice of transfusion medicine”, by undertaking systematic reviews and other evidence-based medicine research projects in the transfusion field. @sritransfusion
- Twitter:
- @sritransfusion
Transfusion Evidence Library
- Twitter:
- @transfusionlib
Stem Cell Evidence
Stem Cell Evidence is a comprehensive collection of high quality research relevant to haematopoietic stem cell transplantation, updated monthly. The most important articles in the field are highlighted in the Stem Cell Evidence Alert which is a newsletter emailed to subscribers. Stem Cell Evidence aims to be a key resource worldwide for medical practitioners, clinical researchers and policy makers. It is also intended to be of value to those planning new clinical trials in the field. It is produced by the Systematic Review Initiative and funded by the UK Blood Services and Oxford Biomedical Research Centre.
- Twitter:
- @evidencestemc
