Talking Transfusion Podcast
On October 17, 2024, the TER coordinators Allison Mo, Susan Brunskill, Catherine Kimber and their invited reviewer guests recorded a podcast where they chatted about the selected papers and the topic of the Round-up.
Introduction
Welcome to the quarterly Transfusion Evidence Round-Up.
This is a collaboration between the International Society of Blood Transfusion (ISBT) and the Transfusion Evidence Library (TEL). We aim to highlight high quality evidence randomised controlled trials and systematic reviews about an internationally relevant subject in the field of Transfusion Medicine. All references are drawn from the Transfusion Evidence Library and, where relevant, Stem Cell Evidence.
This Transfusion Evidence Round-Up is sent to ISBT members and TEL subscribers, so if you are a subscriber to both mailing lists and receive it twice please bear with us until we can resolve this.
The Transfusion Evidence Library is produced by the Systematic Review Initiative (SRI) and funded by the four UK blood services. It is available free at the point of access providing a comprehensive and up-to-date database of high quality evidence in Transfusion Medicine.
Top 10 articles
The following 10 articles were selected from the Transfusion Evidence Library by 3 reviewers: Amita Radhakrishnan Nair, Harriet Tucker and Victor Lin.
Top article
Pelvic packing or endovascular interventions: Which should be given priority in managing hemodynamically unstable pelvic fractures? A systematic review and a meta-analysis. Zhang, D., et al. (2024). Surgery Open Science.
Selected articles
The efficacy and safety of pre-hospital plasma in patients at risk for hemorrhagic shock: an updated systematic review and meta-analysis of randomized controlled trials. Abuelazm, M., et al. (2024). European Journal of Trauma and Emergency Surgery.
Prehospital tranexamic acid in trauma patients: a systematic review and meta-analysis of randomized controlled trials. Acharya, P., et al. (2023). Frontiers in Medicine.
Management of non-compressible torso hemorrhage of the abdomen in civilian and military austere environments: a scoping review. Adams, D., et al. (2024). Trauma Surgery & Acute Care Open.
Efficacy and safety of early administration of 4-factor prothrombin complex concentrate in patients with trauma at risk of massive transfusion: the PROCOAG randomized clinical trial. Bouzat, P., et al. (2023). JAMA.
Prothrombin complex concentrate (PCC) for treatment of trauma-induced coagulopathy: systematic review and meta-analyses. Hannadjas I., et al. (2023). Critical Care.
Emergency department resuscitative endovascular balloon occlusion of the aorta in trauma patients with exsanguinating hemorrhage: the UK-REBOA randomized clinical trial. Jansen J.O., et al. (2023). JAMA.
Predicting blood transfusion following traumatic injury using machine learning models: a systematic review and narrative synthesis. Oakley W., et al. (2024). The Journal of Trauma and Acute Care Surgery.
Early cold stored platelet transfusion following severe injury: a randomized clinical trial. Sperry, J.L., et al. (2024). Annals of Surgery.
Efficacy and safety of tranexamic acid in acute traumatic brain injury: a meta-analysis of randomized controlled trials. Zhang, M., and Liu, T., (2024). The American Journal of Emergency Medicine.
Editorial Board
Amita Radhakrishnan Nair
Area of interest: Blood donor motivation and recruitment, Clinical Transfusion Medicine, Patient Blood Management and Quality Assurance Program in Transfusion Medicine.R
esearch: 2 extramural funded research projects from the Department of Science and Technology, Government of India, 2 Design Registrations filed.
Publications: 25 publications in national and international journals
Awards: President’s Award 2022, from AABB (Association for Advancement of Blood and Biotherapies, USA) and Prof J G Jolly Award 2022 from Indian Society of Blood Transfusion and Immunohematology, SCITMST Certificate of Excellence 2023
Harriet Tucker
Harriet Tucker trained at Oxford University, moved to London for Emergency Medicine training, spent two years working in a retrieval and transfer service and undertaking an MSc in trauma sciences before completing pre-hospital emergency medicine subspecialty training at AACKSS.
She is now a consultant in pre-hospital medicine emergency medicine (KSS, clinical governance lead) and emergency medicine (SGH, where she is Emergency Department lead for major trauma and trust trauma clinical governance lead). She has undertaken a PhD in pre-hospital whole blood transfusion, is a senior lecturer in Pre-hospital critical care (SGUL) and in resuscitation sciences MSc (QMUL) and completed a London Helicopter Emergency Medical Service secondment in 2023.
Victor Lin
Victor Lin is an incoming Haematology Advanced Trainee based at the Royal Melbourne Hospital and Peter MacCallum Cancer Centre in Melbourne, Australia, with a keen interest in all aspects of haematology. After obtaining a Bachelor of Biomedicine and Doctor of Medicine from the University of Melbourne as a Chancellor's Scholar, he completed additional master's degrees in public health and critical care medicine at the University of Sydney, while undergoing his basic physician training. A former Metcalf Scholar in the Cancer and Haematology Division at the Walter and Eliza Hall Institute of Medical Research and honorary clinical researcher in the Transfusion Research Unit at Monash University, he currently works as an honorary clinical researcher in the Department of Haematology at the Peter MacCallum Cancer Centre, and is passionate about advancing the frontier of haematology to improve outcomes for patients with serious blood disorders. Active in the not-for-profit sector, Victor is co-founder of the Young Australian's Cancer Initiative, the Australian Students' Society of Haematology, and Teaching for Impact, and has been named the 2023 Victorian Young Achiever of the Year."
Systematic Research Initiative
The Systematic Review Initiative (SRI) is a clinical research group established in 2001 by NHS Blood and Transplant (NHSBT) and funded by the UK Blood Services. The primary objective of the SRI is to “develop the evidence base for the practice of transfusion medicine”, by undertaking systematic reviews and other evidence-based medicine research projects in the transfusion field. @sritransfusion
- Twitter:
- @sritransfusion
Transfusion Evidence Library
The Transfusion Evidence Library is a database of systematic reviews and randomised controlled trials relevant to transfusion medicine. It is fully searchable, updated monthly and aims to be a key resource for medical practitioners, policy makers and researchers both in the UK and around the world. A monthly email: The Transfusion Evidence Alert with the latest top 10 records is sent to subscribers. The library is produced by the Systematic Review Initiative and funded by the UK Blood Services.
- Twitter:
- @transfusionlib
Stem Cell Evidence
Stem Cell Evidence is a comprehensive collection of high quality research relevant to haematopoietic stem cell transplantation, updated monthly. The most important articles in the field are highlighted in the Stem Cell Evidence Alert which is a newsletter emailed to subscribers. Stem Cell Evidence aims to be a key resource worldwide for medical practitioners, clinical researchers and policy makers. It is also intended to be of value to those planning new clinical trials in the field. It is produced by the Systematic Review Initiative and funded by the UK Blood Services and Oxford Biomedical Research Centre.
- Twitter:
- @evidencestemc
